In addition to this page you can also look into Pubmedia’s database (direct link).

Recent publications

2017

Fernández M, Matilla MA, Ortega Á, Krell T. (2017) Metabolic Value Chemoattractants Are Preferentially Recognized at Broad Ligand Range Chemoreceptor of Pseudomonas putida KT2440. Front Microbiol. 31;8:990

Matilla MA, Krell T. (2017) Chemoreceptor-based signal sensing. Curr Opin Biotechnol. 45:8-14. 

Corral Lugo A, Daddaoua A, Ortega A, Morel B, Díez Peña AI, Espinosa-Urgel M, Krell T. (2017) Purification and characterization of Pseudomonas aeruginosa LasR expressed in acyl-homoserine lactone free Escherichia coli cultures.Protein Expr Purif. 130:107-114. 

Bueno E, Robles EF, Torres MJ, Krell T, Bedmar EJ, Delgado MJ, Mesa S. (2017) Disparate response to microoxia and nitrogen oxides of the Bradyrhizobium japonicum napEDABC, nirK and norCBQD denitrification genes. Nitric Oxide. 3. pii: S1089-8603(16)30224-5. 

Reyes-Darias JA, Krell T. (2017) Riboswitches as Potential Targets for the Development of Anti-Biofilm Drugs. Curr Top Med Chem. 17, 1945-1953

Matilla MA, Udaondo Z, Krell T, Salmond GP. (2017) Genome Sequence of Serratia marcescens MSU97, a Plant-Associated Bacterium That Makes Multiple Antibiotics. Genome Announc. 5. pii: e01752-16.

2016

Rico-Jiménez M, Reyes-Darias JA, Ortega Á, Díez Peña AI, Morel B, Krell T. (2016) Two different mechanisms mediate chemotaxis to inorganic phosphate in Pseudomonas aeruginosa. Scientific Reports 6:28967.

Martín-Mora D, Ortega A, Reyes-Darias JA, García V, López-Farfán D, Matilla MA, Krell T. (2016) Identification of a Chemoreceptor in Pseudomonas aeruginosa That Specifically Mediates Chemotaxis Toward α-Ketoglutarate. Front Microbiol. 7:1937. eCollection 2016.

López-Farfán D, Reyes-Darias JA, Krell T. (2016) The expression of many chemoreceptor genes depends on the cognate chemoeffector as well as on the growth medium and phase. Curr Genet. 2016 

Fernández M, Morel B, Ramos JL and Krell T (2016) “The paralogous ArsR1 and ArsR2 regulators of Pseudomonas putida KT2440 as basis for arsenic biosensor development”. Appl. Environ. Microbiol. 82:4133-44.

Matilla MA, Drew A, Udaondo Z, Krell T and Salmond GP (2016) “Genome Sequence of Serratia plymuthica A153, a Model Rhizobacterium for the Investigation of the Synthesis and Regulation of Haterumalides, Zeamine, and Andrimid”. Genome Announc. 4(3). pii: e00373-16. doi: 10/1128/genomeA.00373-16.

Corral-Lugo A, Daddaoua A, Ortega A, Espinosa-Urgel M and Krell T (2016) “So different and still so similar: The plant compound rosmarinic acid mimics bacterial homoserine lactone quorum sensing signals”. Commun Integr Biol 9(2): e1156832. doi: 10.1080/19420889.2016.1156832

Matilla MA, Nogellova V, Morel B, Krell T, Salmond GP (2016) “Biosynthesis of the acetyl-CoA carboxylase-inhibiting antibiotic, andrimid, in Serratia is regulated by Hfq and the LysR-type transcriptional regulator, AdmX” Environ Microbiol. 18:3635-3650.

Martín-Mora D, Reyes-Darias JA, Ortega A, Corral-Lugo A, Matilla MA, Krell T. (2016) McpQ is a specific citrate chemoreceptor that responds preferentially to citrate/metal ion complexes. Environ Microbiol.  18:3284-3295.

Corral-Lugo A, Daddaoua A, Ortega A, Espinosa-Urgel M, Krell T. (2016) “Rosmarinic acid is a homoserine lactone mimic produced by plants that activates a bacterial quorum-sensing regulator”. Sci Signal. 9(409):ra1.

Fernández M, Morel B, Corral-Lugo A, Rico-Jiménez M, Martín-Mora D, López-Farfán D, Reyes-Darias JA, Matilla MA, Ortega Á, Krell T. (2016) “Identification of ligands for bacterial sensor proteins”. Curr Genet. 62(1):143-7.

Fernández M, Morel B, Corral-Lugo A, Krell T. (2016) “Identification of a chemoreceptor that specifically mediates chemotaxis toward metabolizable purine derivatives”. Mol Microbiol. 99(1):34-42.

Corral-Lugo A, de la Torre J, Matilla MA, Fernández M, Morel B, Espinosa-Urgel M, Krell T. (2015) “Assessment of the contribution of chemoreceptor-based signaling to biofilm formation” Environ Microbiol. 18:3355-3372.

2015

García V, Reyes-Darias JA, Martín-Mora D, Morel B, Matilla MA, Krell T. Identification of a Chemoreceptor for C2 and C3 Carboxylic Acids (2015). Appl Environ Microbiol. 81:5449-57.

Krell T. (2015) Tackling the bottleneck in bacterial signal transduction research: high-throughput identification of signal molecules. Mol. Microbiol. 96: 685-8.

Reyes-Darias JA, García V, Rico-Jiménez M, Corral-Lugo A, Lesouhaitier O, Juárez-Hernández D, Yang Y, Bi S, Feuilloley M, Muñoz-Rojas J, Sourjik V, Krell T. (2015). Specific gamma-aminobutyrate (GABA) chemotaxis in Pseudomonads with different lifestyle. Mol. Microbiol. 97:488-501.

Silva-Jiménez H, Ortega Á, García-Fontana C, Ramos JL, Krell T. (2015) Multiple signals modulate the activity of the complex sensor kinase TodS. Microb Biotechnol. 8: 103-15.

Reyes-Darias JA, Yang Y, Sourjik V, Krell T. (2015) Correlation between signal input and output in PctA and PctB amino acid chemoreceptor of Pseudomonas aeruginosa.Mol. Microbiol. 96: 513-525.

Sampedro I, Parales RE, Krell T, Hill JE. (2015) Pseudomonas Chemotaxis. FEMS Microbiol Rev. 39:17-46.

2014

Mayola A, Irazoki O, Martínez IA, Petrov D, Menolascina F, Stocker R, Reyes-Darias JA, Krell T, Barbé J, Campoy S. (2014) RecA Protein Plays a Role in the Chemotactic Response and Chemoreceptor Clustering of Salmonella enterica. PLoS One. 9(8):e105578.

Ortega A, Krell T. (2014) The HBM domain: Introducing bimodularity to bacterial sensing. Protein Sci. 23: 332-336 

Ortega-González M, Sánchez de Medina F, Molina-Santiago C, López-Posadas R, Pacheco D, Krell T, Martínez-Augustin O, Abdelali D. (2014) Fructooligosacharides Reduce Pseudomonas aeruginosa PAO1 Pathogenicity through Distinct Mechanisms. PLoS One. doi: 10.1371/journal.pone.0085772.

Molina-Santiago C., Daddaoua A., Fillet S., Krell T., Morel B., Duarte E., Ramos J.L. (2014) Identification of new residues involved in intramolecular signal transmission in a prokaryotic transcriptional repressor. J Bacteriol. 196(3): 588-594.

Daddaoua A, Molina-Santiago C, la Torre JD, Krell T, Ramos JL (2014) GtrS and GltR form a two-component system: the central role of 2-ketogluconate in the expression of exotoxin A and glucose catabolic enzymes in Pseudomonas aeruginosa. Nucleic Acids Res., PMID: 24920832

Chavarría M, Durante-Rodríguez G, Krell T, Santiago C, Brezovsky J, Damborsky J, de Lorenzo V. (2014) Fructose 1-phosphate is the one and only physiological effector of the Cra (FruR) regulator of Pseudomonas putida.FEBS Open Bio. 4:377-86.

Krell T, Lacal J, García-Fontana C, Silva-Jiménez H, Rico-Jiménez M, Lugo AC, Darias JA, Ramos JL. (2014) Characterization of molecular interactions using isothermal titration calorimetry. Methods Mol. Biol. 1149:193-203.

Darias JA, García-Fontana C, Lugo AC, Rico-Jiménez M, Krell T. (2014) Qualitative and quantitative assays for flagellum-mediated chemotaxis. Methods Mol. Biol. 1149:87-97.

García-Fontana C, Corral Lugo A, Krell T. (2014) Specificity of the CheR2 methyltransferase in Pseudomonas aeruginosa is directed by a C-terminal pentapeptide in the McpB chemoreceptor. Science Signal.7:ra34.

2013

Rico-Jiménez M., Muñoz-Martínez F., Krell T., Gavira JA., Pineda-Molina E.(2013) Purification, crystallization and preliminary crystallographic analysis of the ligand-binding regions of the PctA and PctB chemoreceptors from Pseudomonas aeruginosa in complex with amino acids. Acta Crystallogr Sect F Struct Biol Cryst Commun. 69(Pt 12): 1431-5.

Sevilla E., Alvarez-Ortega C., Krell T., Rojo F. (2013) The Pseudomonas putida HskA hybrid sensor kinase responds to redox signals and contributes to the adaptation of the electron transport chain composition in response to oxygen availability. Environ Microbiol Rep. 5(6): 825-34.

Daddaoua A., Krell T., Ramos J.L. (2013) Transcriptional control by two interacting regulatory proteins: identification of the PtxS binding site at PtxR. Nucleic Acids Res. 41(22): 10150-6.

Rico-Jiménez M., Muñoz-Martínez F., García-Fontana C., Fernandez M., Morel B., Ortega A., Ramos J.L., Krell T. (2013) Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non-protein amino acid gamma-aminobutyrate (GABA). Mol. Microbiol. 88 (6): 1230-1243.

Garcia-Fontana C., Reyes-Darias J.A., Munoz-Martinez F., Alfonso C., Morel B., Ramos J.L., Krell T. (2013) High specificity in CheR methyltransferase function: CheR2 of Pseudomonas putida is essential for chemotaxis whereas CheR1 is involved in biofilm formation. J. Biol. Chem. 288 (26): 18987-99.

Sevilla E, Silva-Jiménez H, Duque E, Krell T, Rojo F. (2013) The Pseudomonas putida HskA hybrid sensor kinase controls the composition of the electron transport chain. Environ Microbiol Rep. 5: 291-300

Lacal, J., Reyes-Darias, J. A. García-Fontana, C., Ramos, J.L., Krell, T. (2013) Tactic responses to pollutants and its potential to increase biodegradation efficiency. J. Appl. Microbiol. 114: 923-33.

Krell, T., Lacal, J., Reyes-Darias, J. A., Jimenez-Sanchez, C., Sungthong, R., and Ortega-Calvo, J. J. (2013) Bioavailability of pollutants and chemotaxis, Current opinion in biotechnology. 24 (3): 451-456.

2012

Pineda-Molina, E., Reyes-Darias, J.A., Lacal, J., Ramos, J.L., García-Ruiz, J.M., Gavira, J.A., Krell, T. (2012) Evidence for chemoreceptors with bimodular ligand binding regions harboring two signal-binding sites. Proc. Acad. Natl. Sci. USA. 109, 18926-18931.

Pineda-Molina E., Daddaoua A., Krell T., Ramos J. L., Garcia-Ruiz J.M. and Gavira J.A. In situ X-ray data collection of highly sensitive crystals of P. putida PtxS in complex with DNA. Acta cryst. Section F. 68, 1307-1310.

Muñoz-Martínez, F., García-Fontana, C., Rico-Jiménez, M., Alfonso, C. and Krell, T. (2012) Genes Encoding Cher-TPR Fusion Proteins Are Predominantly Found in Gene Clusters Encoding Chemosensory Pathways with Alternative Cellular Functions. PLoS One 7(9):e45810

Udaondo, Z., Duque, E., Fernandez, M., Molina, L., Torre Jde, L., Bernal, P., Niqui, J. L., Pini, C., Roca, A., Matilla, M. A., Antonia Molina-Henares, M., Silva-Jimenez, H., Navarro-Aviles, G., Busch, A., Lacal, J., Krell, T., Segura, A., and Ramos, J. L. (2012) Analysis of solvent tolerance in Pseudomonas putida DOT-T1E based on its genome sequence and a collection of mutants, FEBS letters 586, 2932-2938.

Segura, A., Molina, L., Fillet, S., Krell, T., Bernal, P., Munoz-Rojas, J., and Ramos, J. L. (2012) Solvent tolerance in Gram-negative bacteria, Current opinion in biotechnology 23, 415-421.

Santamaria-Hernando, S., Krell, T., and Ramos-Gonzalez, M. I. (2012) Identification of a novel calcium binding motif based on the detection of sequence insertions in the animal peroxidase domain of bacterial proteins, PloS one 7, e40698.

Gavira, J. A., Lacal, J., Ramos, J. L., Garcia-Ruiz, J. M., Krell, T., and Pineda-Molina, E. (2012) Crystallization and crystallographic analysis of the ligand-binding domain of the Pseudomonas putida chemoreceptor McpS in complex with malate and succinate, Acta cryst. Section F, Structural biology and crystallization communications 68, 428-431.

Daddaoua, A., Fillet, S., Fernandez, M., Udaondo, Z., Krell, T., and Ramos, J. L. (2012) Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS, PloS one 7, e39390.

Krell T, Lacal J, Guazzaroni ME, Busch A, Silva-Jiménez H, Fillet S, Reyes-Darías JA, Muñoz-Martínez F, Rico-Jiménez M, García-Fontana C, Duque E, Segura A, Ramos JL. (2012) Responses of Pseudomonas putida to toxic aromatic carbon sources. Journal of Biotechnology 160, 25-32

Silva-Jiménez H, Ramos JL, Krell T. (2012) Construction of a prototype two-component system from the phosphorelay system TodS/TodT. Protein Eng Des Sel. 25:159-69.

Silva-Jimenez, H., Garcia-Fontana, C., Cadirci, B. H., Ramos-Gonzalez, M. I., Ramos, J. L., and Krell, T. (2012) Study of the TmoS/TmoT two-component system: towards the functional characterization of the family of TodS/TodT like systems, Microbial biotechnology 5, 489-500.

Arce-Rodriguez, A., Durante-Rodriguez, G., Platero, R., Krell, T., Calles, B., and de Lorenzo, V. (2012) The Crp regulator of Pseudomonas putida: evidence of an unusually high affinity for its physiological effector, cAMP, Environ Microbiol. 14: 702-13.

2011

Chavarria, M., Santiago, C., Platero, R., Krell, T., Casasnovas, J. M., and de Lorenzo, V. (2011) Fructose 1-phosphate is the preferred effector of the metabolic regulator Cra of Pseudomonas putida, J Biol Chem 286, 9351-9359.

Desbat, B., Lancelot, E., Krell, T., Nicolai, M. C., Vogel, F., Chevalier, M., and Ronzon, F. (2011) Effect of the beta-Propiolactone Treatment on the Adsorption and Fusion of Influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 Virus H1N1 on a Dimyristoylphosphatidylcholine/Ganglioside GM3 Mixed Phospholipids Monolayer at the Air-Water Interface, Langmuir 27, 13675-13683.

Fillet, S., Krell, T., Morel, B., Lu, D., Zhang, X., and Ramos, J. L. (2011) Intramolecular signal transmission in a tetrameric repressor of the IclR family, Proc Natl Acad Sci U S A 108, 15372-15377.

Guichard, P., Krell, T., Chevalier, M., Vaysse, C., Adam, O., Ronzon, F., and Marco, S. (2011) Three dimensional morphology of rabies virus studied by cryo-electron tomography, J Struct Biol 176, 32-40.

Krell, T., Lacal, J., Munoz-Martinez, F., Reyes-Darias, J. A., Cadirci, B. H., Garcia-Fontana, C., and Ramos, J. L. (2011) Diversity at its best: bacterial taxis, Environ Microbiol 13, 1115-1124.

Lacal, J., Munoz-Martinez, F., Reyes-Darias, J. A., Duque, E., Matilla, M., Segura, A., Calvo, J. J., Jimenez-Sanchez, C., Krell, T., and Ramos, J. L. (2011a) Bacterial chemotaxis towards aromatic hydrocarbons in Pseudomonas, Environ Microbiol 13, 1733-1744.

Lacal, J., Garcia-Fontana, C., Callejo-Garcia, C., Ramos, J. L., and Krell, T. (2011b) Physiologically relevant divalent cations modulate citrate recognition by the McpS chemoreceptor, J Mol Recognit 24, 378-385.

Molina, L., Duque, E., Gomez, M. J., Krell, T., Lacal, J., Garcia-Puente, A., Garcia, V., Matilla, M. A., Ramos, J. L., and Segura, A. (2011) The pGRT1 plasmid of Pseudomonas putida DOT-T1E encodes functions relevant for survival under harsh conditions in the environment, Environ Microbiol. 13, 2315-2327

Moreno, N., Chevalier, M., Ronzon, F., Manin, C., Dupuy, M., Krell, T., and Rieu, J. P. (2011) Unbinding forces of single pertussis toxin-antibody complexes measured by atomic force spectroscopy correlate with their dissociation rates determined by surface plasmon resonance, J Mol Recognit 24, 1105-1114.

Ramos, J. L., Marques, S., van Dillewijn, P., Espinosa-Urgel, M., Segura, A., Duque, E., Krell, T., Ramos-Gonzalez, M. I., Bursakov, S., Roca, A., Solano, J., Fernadez, M., Niqui, J. L., Pizarro-Tobias, P., and Wittich, R. M. (2011) Laboratory research aimed at closing the gaps in microbial bioremediation, Trends Biotechnol 29, 641-647.

2010

Busch, A., Lacal, J., Silva-Jimenez, H., Krell, T., and Ramos, J. L. (2010) Catabolite repression of the TodS/TodT two-component system and effector-dependent transphosphorylation of TodT as the basis for toluene dioxygenase catabolic pathway control, J Bacteriol 192, 4246-4250.

Daddaoua, A., Krell, T., Alfonso, C., Morel, B., and Ramos, J. L. (2010) Compartmentalized glucose metabolism in Pseudomonas putida is controlled by the PtxS repressor, J Bacteriol 192, 4357-4366.

Daniels, C., Krell, T., Michan, C., and Ramos, J. L. (2010) Struggling to get a universal meningococcal vaccine and novel uses for bacterial toxins in cancer treatment, Microb Biotechnol 3, 359-361.

Krell, T., Lacal, J., Busch, A., Silva-Jimenez, H., Guazzaroni, M. E., and Ramos, J. L. (2010) Bacterial sensor kinases: diversity in the recognition of environmental signals, Annu Rev Microbiol 64, 539-559.

Lacal, J., Alfonso, C., Liu, X., Parales, R. E., Morel, B., Conejero-Lara, F., Rivas, G., Duque, E., Ramos, J. L., and Krell, T. (2010a) Identification of a chemoreceptor for tricarboxylic acid cycle intermediates: differential chemotactic response towards receptor ligands, J Biol Chem 285, 23126-23136.

Lacal, J., Garcia-Fontana, C., Munoz-Martinez, F., Ramos, J. L., and Krell, T. (2010b) Sensing of environmental signals: classification of chemoreceptors according to the size of their ligand binding regions, Environ Microbiol 12, 2873-2884.

Lu, D., Fillet, S., Meng, C., Alguel, Y., Kloppsteck, P., Bergeron, J., Krell, T., Gallegos, M. T., Ramos, J., and Zhang, X. (2010) Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators, Genes Dev 24, 2556-2565.

2009

Busch, A., Guazzaroni, M. E., Lacal, J., Ramos, J. L., and Krell, T. (2009) The sensor kinase TodS operates by a multiple step phosphorelay mechanism involving two autokinase domains, J Biol Chem 284, 10353-10360.

Daddaoua, A., Krell, T., and Ramos, J. L. (2009) Regulation of glucose metabolism in Pseudomonas: the phosphorylative branch and entner-doudoroff enzymes are regulated by a repressor containing a sugar isomerase domain, J Biol Chem 284, 21360-21368.

Daniels, C., Michan, C., Krell, T., Roca, A., and Ramos, J. L. (2009) The heat, drugs and knockout systems of microbial biotechnology, Microb Biotechnol 2, 598-600.

Herrera, M. C., Krell, T., Zhang, X., and Ramos, J. L. (2009) PhhR binds to target sequences at different distances with respect to RNA polymerase in order to activate transcription, J Mol Biol 394, 576-586.

Ramos, J. L., Krell, T., Daniels, C., Segura, A., and Duque, E. (2009) Responses of Pseudomonas to small toxic molecules by a mosaic of domains, Curr Opin Microbiol 12, 215-220.

2008

Barranco-Medina, S., Krell, T., Bernier-Villamor, L., Sevilla, F., Lazaro, J. J., and Dietz, K. J. (2008) Hexameric oligomerization of mitochondrial peroxiredoxin PrxIIF and formation of an ultrahigh affinity complex with its electron donor thioredoxin Trx-o, J Exp Bot 59, 3259-3269.

Krell, T. (2008) Microcalorimetry: a response to challenges in modern biotechnology, Microb Biotechnol 1, 126-136.

Lacal, J., Guazzaroni, M. E., Busch, A., Krell, T., and Ramos, J. L. (2008a) Hierarchical binding of the TodT response regulator to its multiple recognition sites at the tod pathway operon promoter, J Mol Biol 376, 325-337.

Lacal, J., Guazzaroni, M. E., Gutierrez-del-Arroyo, P., Busch, A., Velez, M., Krell, T., and Ramos, J. L. (2008b) Two levels of cooperativeness in the binding of TodT to the tod operon promoter, J Mol Biol 384, 1037-1047.

2007

Alguel, Y., Meng, C., Teran, W., Krell, T., Ramos, J. L., Gallegos, M. T., and Zhang, X. (2007) Crystal structures of multidrug binding protein TtgR in complex with antibiotics and plant antimicrobials, J Mol Biol 369, 829-840.

Barranco-Medina, S., Krell, T., Finkemeier, I., Sevilla, F., Lazaro, J. J., and Dietz, K. J. (2007) Biochemical and molecular characterization of the mitochondrial peroxiredoxin PsPrxII F from Pisum sativum, Plant Physiol Biochem 45, 729-739.

Busch, A., Lacal, J., Martos, A., Ramos, J. L., and Krell, T. (2007) Bacterial sensor kinase TodS interacts with agonistic and antagonistic signals, Proc Natl Acad Sci U S A 104, 13774-13779.

Guazzaroni, M. E., Gallegos, M. T., Ramos, J. L., and Krell, T. (2007a) Different modes of binding of mono- and biaromatic effectors to the transcriptional regulator TTGV: role in differential derepression from its cognate operator, J Biol Chem 282, 16308-16316.

Guazzaroni, M. E., Krell, T., Gutierrez del Arroyo, P., Velez, M., Jimenez, M., Rivas, G., and Ramos, J. L. (2007b) The transcriptional repressor TtgV recognizes a complex operator as a tetramer and induces convex DNA bending, J Mol Biol 369, 927-939.

Krell, T., Teran, W., Mayorga, O. L., Rivas, G., Jimenez, M., Daniels, C., Molina-Henares, A. J., Martinez-Bueno, M., Gallegos, M. T., and Ramos, J. L. (2007) Optimization of the palindromic order of the TtgR operator enhances binding cooperativity, J Mol Biol 369, 1188-1199.

Teran, W., Felipe, A., Fillet, S., Guazzaroni, M. E., Krell, T., Ruiz, R., Ramos, J. L., and Gallegos, M. T. (2007) Complexity in efflux pump control: cross-regulation by the paralogues TtgV and TtgT, Mol Microbiol 66, 1416-1428.

2006

Krell, T., Molina-Henares, A. J., and Ramos, J. L. (2006) The IclR family of transcriptional activators and repressors can be defined by a single profile, Protein Sci 15, 1207-1213.

Lacal, J., Busch, A., Guazzaroni, M. E., Krell, T., and Ramos, J. L. (2006) The TodS-TodT two-component regulatory system recognizes a wide range of effectors and works with DNA-bending proteins, Proc Natl Acad Sci U S A 103, 8191-8196.

Molina-Henares, A. J., Krell, T., Eugenia Guazzaroni, M., Segura, A., and Ramos, J. L. (2006) Members of the IclR family of bacterial transcriptional regulators function as activators and/or repressors, FEMS Microbiol Rev 30, 157-186.

Teran, W., Krell, T., Ramos, J. L., and Gallegos, M. T. (2006) Effector-repressor interactions, binding of a single effector molecule to the operator-bound TtgR homodimer mediates derepression, J Biol Chem 281, 7102-7109.